The strategy of closing businesses and advising residents to stay at home is, by design, isolating. That’s good for limiting the damage that the coronavirus known as COVID-19 is able to inflict in our communities. Isolation, however, comes at a cost. In the best of circumstances, restrictions on where you can go, what you can do, and who you can see in person would be hard to deal with. The stress of a new, fast-spreading illness and uncertainty about the future make it even more troubling. How can these changes in our daily lives affect our health?